产品货号：
Z19231
中文名称：
LAG3抗体
英文名称：
Anti-LAG3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LAG3 Antibody |
| 指标别名 | CD223;FDC;LAG3;LAG-3;lymphocyte activation gene 3;Protein FDC |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | LAG3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LAG3 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human LAG3.The immunogen is located within amino acids 110 - 160 of LAG3. |
| 计算分子量 | 57kDa |
| 成分 | LAG3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LAG3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1),negatively regulating T-cell function and homeostasis (2).It is expressed in B,T,and NK cells,monocytes,and dendritic cells (3),and acts to regulate T cell expansion (4).LAG3 is also an important immune checkpoint protein,with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions.Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1,suggesting that a dual antibody approach may prove useful in cancer immunotherapy (5). |
| Uniprot ID | P18627 |
| 基因名全称 | Lymphocyte activating 3 |
| 蛋白名全称 | Lymphocyte activating 3 |
| 推荐稀释比 | LAG3 antibody can be used for Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry at 5μg/mL.For Immunoflorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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